Ultrasound Guided PRP & A2M Injection for Knee, Shoulder, Hip, Elbow, Wrist, Ankle, Spine (SI joints, Facet), Tendons , Sport Injuries, and other Musculoskeletal conditions 


Struggling with chronic back, knee, shoulder, hip pain or another joint/tendon injury? Ultrasound guided PRP therapy( with or without A2M*) can provide natural pain relief and accelerate healing in joints, tendons, and soft tissues. Whether you're dealing with early stages of osteoarthritis, tendonitis, Tendon Tear, Meniscus tear or an injury, PRP may promote tissue repair and reduces inflammation, helping you regain mobility and comfort. With minimal downtime and long-lasting results, PRP is a powerful alternative to some traditional treatments like corticosteroids or some surgeries.

*A2M= Alpha-2-Macroglobulin

Book your free phone consultation by our board certified provider and to see if PRP or other regenerative injection is advisable for your condition.

How PRP Works:

  1. Blood Draw: A small amount of blood is drawn from the patient’s arm, similar to a routine blood test.(At SD PRP Clinic, we may draw 30-120 ML of blood depending on what we treat, 60 ML for most.)
  2. Centrifugation: The blood is then placed in a special kit and a centrifuge, which spins it rapidly to separate its components. This process concentrates the platelets, which are the cells involved in healing and tissue regeneration.( We use the best available FDA-Cleared Kits, i.e EmCyte SP kits)
  3. Injection: The concentrated platelet-rich plasma (PRP) is injected under the ultrasound guidance into the area that causing pain, usually near the damaged tissue (like cartilage, tendons, or ligaments).

Potential Benefits:

  1. Pain Reduction: PRP has been shown to reduce pain and inflammation in conditions like osteoarthritis or tendon injuries, making it an appealing option for those with chronic Joint/tendon pain.
  2. Healing Promotion: The growth factors in platelets may help accelerate the healing of damaged tissues, including cartilage or soft tissue in the knee or shoulder, and other joints and tendons.
  3. Improved Mobility: Many patients may experience improved joint function and range of motion after PRP therapy, which can lead to better quality of life and a reduction in the need for surgery.

Conditions PRP -A2M Might Help:

  • Osteoarthritis: Particularly in the early or mid-stages, PRP with A2M may help reduce pain and slow down the progression of cartilage degeneration. PRP is not advised in servers osteoarthritis warranted a joint replacement surgery (can be tried if surgery is not possible).
  • Tendinitis/Tendinosis: PRP is used to treat tendon injuries. For example in the knee when there is a patellar tendinitis, or in elbow for tennis elbow
  • Ligament Injuries/Partial tendon tear: Studies suggest PRP can help heal knee ligament injuries and heal partial tendon Teras (the evidence is still mixed).


List of major MSK conditions we do ultrasound guided PRP & A2M


  • Tennis Elbow (Lateral epicondylitis)
  • Golfer's Elbow (Medial epicondylitis)
  • Jumper's Knee (Patellar tendonitis)
  • Achilles Tendonitis or tendinopathy
  • Plantar Fasciitis (Chronic heel pain)
  • Rotator Cuff Tendonitis and partial tears
  • Osteoarthritis: Most commonly used for mild-to-moderate osteoarthritis of the kneehip, shoulder, and ankle.
  • Meniscus Tears: Specifically used to promote healing in degenerative or partial tears of the knee cartilage.
  • Labral Tears: Cartilage tears in the shoulder or hip joints.
  • Sacroiliac (SI) Joint Pain: Chronic inflammation or dysfunction in the lower spine/pelvis area. 
  • Chronic Low Back, Neck, Thoracic Pain: Arising from soft-tissue, muscle, or ligamentous strains.
  • Facet Joint Arthritis: Targeting the small stabilizing joints between the vertebrae. 
  • Post-surgical Healing: Applied intraoperatively during orthopedic surgeries (like rotator cuff repairs or ACL reconstructions) to help the repaired graft or tissue fuse and heal faster.
  • Ligament Sprains and Tears: Such as partial tears of the Anterior Cruciate Ligament (ACL) or Medial Collateral Ligament (MCL) in the knee, or the Ulnar Collateral Ligament (UCL) in the elbow.
  • Muscle Strains and Tears and sport injuries : Hamstring strains, calf pulls, or other major muscle belly.
  • AC Joint pain/Arthritis
  • Carpal Tunnel Syndrome and Wrist Pain 
  • Temporomandibular joint (TMJ) disorders
  • Degenerative Disc Disease: We DO NOT inject into disc in this time.  We Do Not perform Epidural injections.
  • Some other musculoskeletal conditions: Please contact us if your condition is not listed above to
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Double-Spin PRP + A2M (The Complete Joint Protocol)

For majority of musculoskeletal conditions and osteoarthritis, SD PRP Clinic introduces Alpha-2-Macroglobulin (A2M) into the healing matrix of double spin PRP.

The Analogy: While PRP is the "construction crew" that rebuilds tissue, A2M is the "security guard" that protects the joint.

The Science: In a damaged or arthritic joint, destructive enzymes (catabolic proteases) constantly chew away at cartilage. A2M is a massive, naturally occurring plasma protein captured during our specialized filtration processing. It acts as a molecular trap, capturing and neutralizing these destructive enzymes.

The Process: This protocol involves a similar but more sophisticated process than double-spin PRP. We utilize a specialized concentrator filter to eliminate excess water, unwanted low-molecular-weight proteins, and residual red blood cells, isolating a highly concentrated dose of pure A2M. By combining Double-Spin PRP with A2M, we jumpstart tissue repair while actively shutting down the chemical processes causing joint degeneration.


Is it Effective?

The effectiveness of PRP can vary depending on many factors. Studies show positive results in reducing pain and improving function. The evidence is still growing, and outcomes can be inconsistent depending on several contributing factors (i.e post procedure resting/activity, the severity of the problem, the patient's overall health, and the technique used).

Considerations:

  • Recovery Time: Since the PRP comes from your own blood, the risk of allergic reaction is low. However, it may take several days/weeks to notice improvements in pain and function, as the body works to heal itself.
  • Multiple Therapies: In many cases, 2-3 injections may be required over a few months.
  • Cost: PRP therapy can be expensive, and it is not covered by insurance.


PRP therapy is considered a relatively low-risk procedure, but it's always best to discuss with your doctor to see if it's a good fit for your specific condition and needs. Our board certified trained provider(s) in SD PRP Clinic can discuss if PRP is the right treatment for you. Please book your free phone consult now!

For any question or concerns, please email us at mysdprp@gmail.com or TEXT/call SD PRP Clinic.